Monday, November 30, 2009

Beclometasone Dipropionate




Beclometasone Dipropionate may be available in the countries listed below.


Ingredient matches for Beclometasone Dipropionate



Beclometasone

Beclometasone Dipropionate (BANM) is also known as Beclometasone (Rec.INN)

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday, November 25, 2009

Disys Plus




Disys Plus may be available in the countries listed below.


Ingredient matches for Disys Plus



Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Disys Plus in the following countries:


  • Bangladesh

Valsartan

Valsartan is reported as an ingredient of Disys Plus in the following countries:


  • Bangladesh

International Drug Name Search

Monday, November 23, 2009

Dextrose and Electrolyte No 48





Dosage Form: injection

in VIAFLEX Plastic Container



Dextrose and Electrolyte No 48 Description


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) is a sterile, nonpyrogenic solution for fluid and electrolyte replenishment and caloric supply in a single dose container for intravenous administration. Each 100 mL contains 5 g Dextrose Hydrous, USP*, 260 mg Sodium Lactate (C3H5NaO3), 141 mg Potassium Chloride, USP (KCl), 31 mg Magnesium Chloride, USP (MgCl2•6H20), 20 mg Monobasic Potassium Phosphate, NF (KH2PO4), and 12 mg Sodium Chloride, USP (NaCl). It contains no antimicrobial agents. pH 5.0 (4.0 to 6.5).



5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) administered intravenously has value as a source of water, electrolytes, and calories. One liter has an ionic concentration of 25 mEq sodium, 20 mEq potassium, 3 mEq magnesium, 24 mEq chloride, 23 mEq lactate and 3 mEq phosphate as HPO4=. The osmolarity is 348 mOsmol/L (calc). Normal physiologic osmolarity range is approximately 280 to 310 mOsmol/L. Administration of substantially hypertonic solutions (≥ 600 mOsmol/L) may cause vein damage. The caloric content is 180 kcal/L.


The VIAFLEX plastic container is fabricated from a specially formulated polyvinyl chloride (PL 146 Plastic). The amount of water that can permeate from inside the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts within the expiration period, e.g., di-2-ethylhexyl phthalate (DEHP), up to 5 parts per million. However, the safety of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by tissue culture toxicity studies.



Dextrose and Electrolyte No 48 - Clinical Pharmacology


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) has value as a source of water, electrolytes and calories. They are capable of inducing diuresis depending on the clinical condition of the patient.


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) produce a metabolic alkalinizing effect. Lactate ions are metabolized ultimately to carbon dioxide and water, which requires the consumption of hydrogen cations.



Indications and Usage for Dextrose and Electrolyte No 48


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) is indicated as a source of water, electrolytes, and calories or as an alkalinizing agent.



Contraindications


Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.



Warnings


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency, and in clinical states in which there exists edema with sodium retention.


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) should be used with great care, if at all, in patients with hyperkalemia, severe renal failure, and in conditions in which potassium retention is present.


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) should be used with great care in patients with metabolic or respiratory alkalosis. The administration of lactate ions should be done with great care in those conditions in which there is an increased level or an impaired utilization of these ions, such as severe hepatic insufficiency.


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) should not be administered simultaneously with blood through the same administration set because of the possibility of pseudoagglutination or hemolysis.


The intravenous administration of 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states, or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentrations of the injection. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of the injection.


In patients with diminished renal function, administration of 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) may result in sodium or potassium retention.


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) is not for use in the treatment of lactic acidosis.



Precautions


Clinical evaluation and periodic laboratory determinations are necessary to monitor changes in fluid balance, electrolyte concentrations, and acid base balance during prolonged parenteral therapy or whenever the condition of the patient warrants such evaluation.


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) should be used with caution. Excess administration may result in metabolic alkalosis.


Caution must be exercised in the administration of these injections to patients receiving corticosteroids or corticotropin.


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) should be used with caution in patients with overt or subclinical diabetes mellitus.



Pregnancy


Teratogenic Effects

Pregnancy Category C


Animal reproduction studies have not been conducted with 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP). It is also not known whether 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) should be given to a pregnant woman only if clearly needed.



Pediatric Use


Safety and effectiveness of 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) in pediatric patients have not been established by adequate and well controlled trials, however, the use of dextrose and electrolytes solutions in the pediatric population is referenced in the medical literature. The warnings, precautions and adverse reactions identified in the label copy should be observed in the pediatric population.


In very low birth weight infants, excessive or rapid administration of dextrose injection may result in increased serum osmolality and possible hemorrhage.



Geriatric Use


Clinical studies of 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.


This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.



Carcinogenesis and Mutagenesis and Impairment of Fertility


Studies with 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) have not been performed to evaluate carcinogenic potential, mutagenic potential, or effects on fertility.



Nursing Mothers


It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when 5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) is administered to a nursing mother.


Do not administer simultaneously with blood. Do not administer unless solution is clear and seal is intact.



Adverse Reactions


Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.


If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.



Dextrose and Electrolyte No 48 Dosage and Administration


As directed by a physician. Dosage is dependent upon the age, weight and clinical condition of the patient as well as laboratory determinations.


Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.


All injections in VIAFLEX plastic containers are intended for intravenous administration using sterile equipment.


As reported in the literature, the dosage and constant infusion rate of intravenous dextrose must be selected with caution in pediatric patients, particularly neonates and low weight infants, because of the increased risk of hyperglycemia/hypoglycemia.


Additives may be incompatible. Complete information is not available.


Those additives known to be incompatible should not be used. Consult with pharmacist, if available. If, in the informed judgment of the physician, it is deemed advisable to introduce additives, use aseptic technique. Mix thoroughly when additives have been introduced. Do not store solutions containing additives.



How is Dextrose and Electrolyte No 48 Supplied


5% Dextrose and Electrolyte No. 48 Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) in VIAFLEX plastic containers is available as shown below:















CodeSize (mL)NDC
2B2102250NDC 0338-0143-02
2B2103500NDC 0338-0143-03
2B21041000NDC 0338-0143-04

Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C); brief exposure up to 40°C does not adversely affect the product.



DIRECTIONS FOR USE OF VIAFLEX PLASTIC CONTAINERS


Warning: Do not use plastic containers in series connections. Such use could result in air embolism due to residual air being drawn in from the primary container before administration of the fluid from the secondary container is completed.



To Open


Tear overwrap down side at slit and remove solution container. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. This is normal and does not affect the solution quality or safety. The opacity will diminish gradually. Check for minute leaks by squeezing inner bag firmly. If leaks are found, discard solution as sterility may be impaired. If supplemental medication is desired, follow directions below.



Preparation for Administration


1. Suspend container from eyelet support.


2. Remove plastic protector from outlet port at bottom of container.


3. Attach administration set. Refer to complete directions accompanying set.



To Add Medication


Warning: Additives may be incompatible.



To add medication before solution administration


1. Prepare medication site.


2. Using syringe with 19 to 22 gauge needle, puncture resealable medication port and inject.


3. Mix solution and medication thoroughly. For high density medication such as potassium chloride, squeeze ports while ports are upright and mix thoroughly.



To add medication during solution administration


1. Close clamp on the set.


2. Prepare medication site.


3. Using syringe with 19 to 22 gauge needle, puncture resealable medication port and inject.


4. Remove container from IV pole and/or turn to an upright position.


5. Evacuate both ports by squeezing them while container is in the upright position.


6. Mix solution and medication thoroughly.


7. Return container to in use position and continue administration.


Baxter Healthcare Corporation


Deerfield, IL 60015 USA


Printed in USA


071947768


07-19-47-768 June 2005


BAXTER, VIAFLEX and PL 146 are trademarks of Baxter International Inc








DEXTROSE AND ELECTROLYTE NO. 48 
sodium lactate, potassium chloride, magnesium chloride, monobasic potassium phosphate, sodium chloride and dextrose monohydrate  injection, solution










Product Information
Product TypeHUMAN PRESCRIPTION DRUGNDC Product Code (Source)0338-0143
Route of AdministrationINTRAVENOUSDEA Schedule    


























INGREDIENTS
Name (Active Moiety)TypeStrength
Dextrose monohydrate (Dextrose)Active5 GRAM  In 100 MILLILITER
Sodium Lactate (Sodium Lactate)Active260 MILLIGRAM  In 100 MILLILITER
Potassium Chloride (Potassium Chloride)Active141 MILLIGRAM  In 100 MILLILITER
Magnesium Chloride (Magnesium Chloride)Active31 MILLIGRAM  In 100 MILLILITER
Monobasic Potassium Phosphate (Monobasic Potassium Phosphate)Active20 MILLIGRAM  In 100 MILLILITER
Sodium Chloride (Sodium Chloride)Active12 MILLIGRAM  In 100 MILLILITER
WaterInactive 


















Product Characteristics
Color    Score    
ShapeSize
FlavorImprint Code
Contains      


















Packaging
#NDCPackage DescriptionMultilevel Packaging
10338-0143-02250 mL (MILLILITER) In 1 BAGNone
20338-0143-03500 mL (MILLILITER) In 1 BAGNone
30338-0143-041000 mL (MILLILITER) In 1 BAGNone

Revised: 05/2007Baxter Healthcare Corporation

More Dextrose and Electrolyte No 48 resources


  • Dextrose and Electrolyte No 48 Drug Interactions
  • Dextrose and Electrolyte No 48 Support Group
  • 0 Reviews · Be the first to review/rate this drug

Sunday, November 22, 2009

Diabetic Ketoacidosis, in DM Type II Medications


There are currently no drugs listed for "Diabetic Ketoacidosis, in DM Type II".

Definition of Diabetic Ketoacidosis, in DM Type II: Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus (DM), or diabetes. It may occur in some people when their diabetes is not well controlled.

Learn more about Diabetic Ketoacidosis, in DM Type II





Drug List:

Wednesday, November 18, 2009

Innosensitive




Innosensitive may be available in the countries listed below.


Ingredient matches for Innosensitive



Alfuzosin

Alfuzosin hydrochloride (a derivative of Alfuzosin) is reported as an ingredient of Innosensitive in the following countries:


  • Greece

International Drug Name Search

Tuesday, November 17, 2009

Delipid




Delipid may be available in the countries listed below.


Ingredient matches for Delipid



Gemfibrozil

Gemfibrozil is reported as an ingredient of Delipid in the following countries:


  • Bangladesh

International Drug Name Search

Sunday, November 15, 2009

Regel-SO




Regel-SO may be available in the countries listed below.


Ingredient matches for Regel-SO



Oxetacaine

Oxetacaine is reported as an ingredient of Regel-SO in the following countries:


  • India

Sucralfate

Sucralfate is reported as an ingredient of Regel-SO in the following countries:


  • India

International Drug Name Search

Friday, November 13, 2009

Balsalazide




In the US, Balsalazide (balsalazide systemic) is a member of the drug class 5-aminosalicylates and is used to treat Crohn's Disease, Ulcerative Colitis and Ulcerative Colitis - Active.

US matches:

  • Balsalazide

  • Balsalazide Disodium

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

A07EC04

CAS registry number (Chemical Abstracts Service)

0080573-04-2

Chemical Formula

C17-H15-N3-O6

Molecular Weight

357

Therapeutic Categories

Anti-inflammatory agent

Gastrointestinal agent

Chemical Names

(E)-5-[[p-[(2-Carboxyethyl)carbamoyl]phenyl]azo]salicylic acid (WHO)

Benzoic acid, 5-[[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]azo]-2-hydroxy-, (E)-

Foreign Names

  • Balsalazidum (Latin)
  • Balsalazid (German)
  • Balsalazide (French)
  • Balsalazida (Spanish)

Generic Names

  • Balsalazide (OS: BAN, DCF)
  • BX 661 A (IS: Biorex)
  • Mesalamine (5-aminosalicylic acid 5-ASA), Prodrug of (IS)
  • Prodrug of Mesalamine (IS: 5-aminosalicylic acid 5-ASA)
  • Balsalazide Disodium (OS: USAN)
  • Balsalazide Sodium (OS: BANM)

Brand Names

  • Balsalazida
    Monte, Argentina


  • Benoquin
    Ivax, Argentina


  • Colazide
    Pharmatel, Australia


  • Intazide
    Intas, India


  • Balsalazide Disodium
    Apotex, United States; Mylan, United States; Roxane, United States


  • Balzide
    Menarini, Italy


  • Basazyde
    Lotus, Taiwan


  • Colazal
    Salix, United States


  • Colazid
    Meda, Sweden; Shire, Norway


  • Colazide
    Almirall, United Kingdom


  • Premid
    Almirall, Denmark

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Sunday, November 8, 2009

Hydrazide




Hydrazide may be available in the countries listed below.


Ingredient matches for Hydrazide



Isoniazid

Isoniazid is reported as an ingredient of Hydrazide in the following countries:


  • Japan

International Drug Name Search

Thursday, November 5, 2009

Semprex-D


Semprex-D is a brand name of acrivastine/pseudoephedrine, approved by the FDA in the following formulation(s):


SEMPREX-D (acrivastine; pseudoephedrine hydrochloride - capsule; oral)



  • Manufacturer: UCB INC

    Approval date: March 25, 1994

    Strength(s): 8MG;60MG [RLD]

Has a generic version of Semprex-D been approved?


No. There is currently no therapeutically equivalent version of Semprex-D available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Semprex-D. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents

There are no current U.S. patents associated with Semprex-D.

See also...

  • Semprex-D Consumer Information (Wolters Kluwer)
  • Semprex-D Consumer Information (Cerner Multum)
  • Acrivastine/Pseudoephedrine Consumer Information (Wolters Kluwer)
  • Acrivastine and pseudoephedrine Consumer Information (Cerner Multum)

Wednesday, November 4, 2009

Deltacal




Deltacal may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Deltacal



Calcium Carbonate

Calcium Carbonate is reported as an ingredient of Deltacal in the following countries:


  • Australia

International Drug Name Search